
I seriously question whether trade shows are the way to go anymore, considering the access retailers have to artists through online venues like etsy, trunkt, wholesalecrafts.com (to name just a few), and the endless "design" blogs. The only question is how do you access retailers if you want to wholesale but aren't ready to gamble baby's college education fund away yet?
Second rule of wholesale: You must invest into marketing your wholesale items if you expect to take wholesale orders. As artists, marketing can be a word we want to pull away from. But marketing can be fun and there are so many ways to approach it that you don't have to turn it into a dreaded chore. But marketing means time, and it means money. And what does marketing mean in this context? Here is my short list of must-have and must-do for artists marketing wholesale:
1) A clear and concise one-sheet with prices and terms.
2) A catalog with images of your work. Don't flip out when I say "catalog" and get all scared you can't afford it. A catalog can be a simple color sheet with thumbnails of your work-- that's what I have, and you can get 250 printed up at PS print for just over $200, and that number lasts me a

3) Create a place online where retailers can access your work and see images. A blog, etsy, and a website are becoming mandatory for people selling their art. I don't think you need all three, but you do need at least one. Make sure these things advertise the fact that you wholesale. For those who simply cannot handle navigating a website yet, I highly recommend using etsy as a launch pad and using their community forums to ask other artists how they are handling website stuff.
4) Wholesale begets more wholesale. Go out and get that first wholesale account, and there is no better place than somewhere in your hometown. Find the perfect store for your work, one that carries handmade work (there is a huge difference between stores that carry imports or factory made work and one that carries American handmade), and pitch them. Retailers need you just as badly as you need them-- they can't stay open if they can't find cool stuff to sell, and they probably don't know you exist! Show them who you are.
5) Read those design blogs and research the stores they cover. I will often send out catalogs to stores I think should carry my work-- or I used to anyway, before I got totally sick of wholesaling. That brought in a few accounts and cost me hardly anything.
There is always the option of hiring a rep too, but if you are considering that you should already be well into the wholesale game. A rep takes 15%, so you need to be able to produce a lot in a short amount of time to make up for their take. Speaking of making a lot in a short amount of time, I'm off to the studio now!